Motilium (Domperidone) 10mg


Motilium (Domperidone) by Janssen Cilag


10 tablets per strip.

Pharmaceutical Grade



Motilium contains the active ingredient Domperidone, which helps bring your stomach’s natural rhythm back to normal and enables food to move through your stomach properly. It relieves the uncomfortable feelings of fullness and bloating and also works on the vomiting centre of the brain to relieve your feelings of nausea.

Motilium works primarily by blocking dopamine receptors found in the upper end of the digestive system. This causes tightening of the muscles at the entry to the stomach, relaxation of the muscles at the exit of the stomach and increased contraction of the muscles in the stomach itself. These actions speed up the passage of food through the stomach into the intestine, which physically helps prevent vomiting and reduces feelings of sickness, bloating and fullness. It also prevents food from flowing the wrong way through the stomach and so prevents reflux (regurgitation of the stomach contents back into the foodpipe).

Motilium suppositories can be useful for people who are being sick and can’t take medicines by mouth, or for people who have difficulty swallowing tablets. The Domperidone is absorbed into the bloodstream through the rich supply of blood vessels found in the rectum.

Side effects are: allergic reactions, stimulating or increasing milk production, by increasing prolactin production by the pituitary gland, such as rash or urticaria, have been reported. Abdominal cramps have also been reported. Motilium side effects like Dystonic reactions (extrapyramidal phenomena) may occur. Motilium side effects like Reversible raised serum prolactin levels have been observed which may lead to galactorrhoea and gynaecomastia.



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